<p>Globally, the hospitality industry became a major service industry that provides larger employment and income opportunities in the hotel service sector, but the hotel workers are still exposed to different types of health risks and injuries due to their heavy workload and lack of proper ergonomic facilities. The study follows a systematic review approach based on PRISMA guidelines and research articles published between 2010 to 2024 from major academic sources that focuses on psychological stress, chemical exposure, working conditions and safety practices in the organizations. The review addressed research gaps like lack of attention to socio-Economic factors and longitudinal health problems faced by hotel workers in the fast-developing region like Tamil Nadu, India. The study emphasises the significant development in occupational health policies, improving the workplace conditions with strong need for future research improving economic and social aspects to provide better and sustainable working environment in the hotel sector.</p>